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Metastasis of the brain

Metastasis of the brain is a common complication of cancer. According to recent statistics, nearly 20% of adult patients with cancer during their lifetime have the primary tumor metastasis to the brain. Metastasis to the brain is a often complication of cancer. Primary frequency detection of metastasis in the brain characterized by significant variability depending on the type of primary tumor; highest frequency observed for lung cancer (20%), and melanoma (7%), kidney cancer (6.5%), breast (5 %) and colorectal cancer (1.8%). The least frequent metastasis to the brain is seen with prostate cancer, malignant tumors of the female reproductive system, head and neck, as well as skin cancer.


Signs of metastatic brain lesions can be divided into systemic and patchy. Focal symptoms, such as hemiparesis, aphasia, visual field loss, may differ with significant variability depending on the location of the tumor. Systemic symptoms such as headache, depression of consciousness (lethargy, stupor , coma) , nausea and vomiting, are the result of increased intracranial pressure (ICP), or hydrocephalus. Metastases paraventricular parts of the brain can cause the development of obstructive hydrocephalus due to disruption of the normal outflow of fluid from the 1H and IV ventricles. Obstructive hydrocephalus is most pronounced in the localization of tumors in the posterior cranial fossa.

Headaches caused by increased intracranial pressure and / or buildup of hydrocephalus, have the following characteristics:

• The most expressed in the morning and in the supine position;

• accompanied by nausea and vomiting;

• increase with coughing and suspense;

• be accompanied by confusion or depression of consciousness.

Increased intracranial pressure is often accompanied by swelling of the optic nerve, but the lack of this feature cannot completely eliminate the increased intracranial pressure.

Methods of treatment:

Microsurgical removal of brain tumors using intra-operative navigation system with endoscopic-assisted

Microsurgical removal of brain tumors using intraoperative neuromonitoring